Dr Gyapong has an interest in health systems, implementation research, Demographic Surveillance, tropical diseases and gender. She has several publications in and is a reviewer for several international journals.
She serves on a number of National and international committees and task forces and has a part time faculty appointment with the University of Ghana, and adjunct professorial appointments with the Brunel University in the UK and Georgetown University in the USA where she serves as an Adjunct Professor in the International Health Program.
Dr Gyapong is the Social Science theme lead in Ghana for the COUNTDOWN programme and leads the social science working group of the INDEPTH Network. In the last 22 years, she has contributed to setting up of the Lymphatic Filariasis Control programme in Ghana, building research capacity for district and regional health management teams. She started and continues to maintain a Health and Demographic Surveillance System in the Dodowa Health Research Centre.